c-Myb and GATA-1 alternate dominant roles during megakaryocyte differentiation.

c-Myb and GATA-1 alternate dominant roles during megakaryocyte differentiation.

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BACKGROUND: Transcription factors are essential for blood cell formation. Mice expressing low levels of c-Myb (c-Myb(low)) have an increased number of bone marrow megakaryocytes (MKs) and corresponding thrombocytosis. In contrast, mice engineered to express low levels of GATA-1 (GATA-1(low)) in the...

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Bibliografiske detaljer
Main Authors:	García, P, Berlanga, O, Vegiopoulos, A, Vyas, P, Frampton, J
Format:	Journal article
Sprog:	English
Udgivet:	2011

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