Extracellular calcium and cAMP: second messengers as "third messengers"?

Extracellular calcium and cAMP: second messengers as "third messengers"?

Calcium and cyclic AMP are familiar second messengers that typically become elevated inside cells on activation of cell surface receptors. This article will explore emerging evidence that transport of these signaling molecules across the plasma membrane allows them to be recycled as "third mess...

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Bibliografiska uppgifter
Huvudupphovsmän: Hofer, A, Lefkimmiatis, K
Materialtyp: Journal article
Språk:English
Publicerad: 2007
Beskrivning
Sammanfattning:Calcium and cyclic AMP are familiar second messengers that typically become elevated inside cells on activation of cell surface receptors. This article will explore emerging evidence that transport of these signaling molecules across the plasma membrane allows them to be recycled as "third messengers," extending their ability to convey information in a domain outside the cell.

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