Understanding the role of RNA nucleases in human disease

Understanding the role of RNA nucleases in human disease

<p>Congenital dyserythropoietic anaemia type-I (CDA-I) is a rare inherited disorder of erythropoiesis, in which patient erythroblasts uniquely display a pathognomonic pattern of heterochromatin, referred to as ‘spongy’ heterochromatin. The molecular basis of CDA-I remains unknown. Most cases o...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Brolih, S
Awduron Eraill:	McHugh, P
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2021

Eitemau Tebyg

Zinc Finger Nucleases as tools to understand and treat human diseases
gan: Stokoe David, et al.
Cyhoeddwyd: (2010-07-01)

Understanding the genetic relationship between key effectors of DNA interstrand crosslink repair
gan: Brolih, S
Cyhoeddwyd: (2016)

Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis
gan: Gabriela Maria Guerra, et al.
Cyhoeddwyd: (2021-11-01)

Optimised oligonucleotide substrates to assay XPF-ERCC1 nuclease activity for the discovery of DNA repair inhibitors
gan: Thomas, A, et al.
Cyhoeddwyd: (2019)

Chemical nucleases are a robust alternative for RNase H cleavage of human ribosomal RNA.
gan: Hagen Wesseling, et al.
Cyhoeddwyd: (2025-01-01)

Targeting human microRNA genes using engineered Tal-effector nucleases (TALENs).
gan: Ruozhen Hu, et al.
Cyhoeddwyd: (2013-01-01)

Viral Nucleases
gan: Zhengqiang Wang, et al.
Cyhoeddwyd: (2023-03-01)

The Transposon-Encoded Protein TnpB is an RNA-Guided Nuclease
gan: Nety, Suchita P.
Cyhoeddwyd: (2023)

DNA targeting specificity of RNA-guided Cas9 nucleases
gan: Hsu, Patrick, et al.
Cyhoeddwyd: (2016)

Efficiency of RNA interference is improved by knockdown of dsRNA nucleases in tephritid fruit flies
gan: Alison Tayler, et al.
Cyhoeddwyd: (2019-12-01)

Highly Sensitive Nuclease Assays Based on Chemically Modified DNA or RNA
gan: Shinobu Sato, et al.
Cyhoeddwyd: (2014-07-01)

Biochemical Comparison of dsRNA Degrading Nucleases in Four Different Insects
gan: Yingchuan Peng, et al.
Cyhoeddwyd: (2018-05-01)

Measuring Real-time DNA/RNA Nuclease Activity through Fluorescence
gan: Paulina Wyrzykowska, et al.
Cyhoeddwyd: (2021-11-01)

Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases
gan: Citorik, Robert James, et al.
Cyhoeddwyd: (2016)

High-efficiency targeted editing of large viral genomes by RNA-guided nucleases.
gan: Yanwei Bi, et al.
Cyhoeddwyd: (2014-05-01)

DNase II Can Efficiently Digest RNA and Needs to Be Redefined as a Nuclease
gan: Jingyun Zhuang, et al.
Cyhoeddwyd: (2024-09-01)

Robust genome and RNA editing via CRISPR nucleases in PiggyBac systems
gan: Yuqian Jiang, et al.
Cyhoeddwyd: (2022-08-01)

DNA Damage Responses Are Induced by tRNA Anticodon Nucleases and Hygromycin B.
gan: Sabrina Wemhoff, et al.
Cyhoeddwyd: (2016-01-01)

The role of electrostatics in colicin nuclease domain translocation into bacterial cells.
gan: Walker, D, et al.
Cyhoeddwyd: (2007)

Nuclease colicins and their immunity proteins.
gan: Papadakos, G, et al.
Cyhoeddwyd: (2012)

Nucleases : molecular biology and applications /
gan: Mishra, N. C. (Nawin C.)
Cyhoeddwyd: (2002)

Simultaneous Extraction of DNA and RNA from Nuclease-Rich Pathogenic Protozoan Trichomonas vaginalis
gan: Chun-Fen Chou, et al.
Cyhoeddwyd: (1996-05-01)

SARS-CoV-2 RNA Detection with Duplex-Specific Nuclease Signal Amplification
gan: Meiqing Liu, et al.
Cyhoeddwyd: (2021-02-01)

Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery
gan: Jiyun Chen, et al.
Cyhoeddwyd: (2024-01-01)

Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity
gan: Lidiya Lisitskaya, et al.
Cyhoeddwyd: (2022-08-01)

Targeted Mutagenesis in Plant Cells through Transformation of Sequence-Specific Nuclease mRNA.
gan: Thomas J Stoddard, et al.
Cyhoeddwyd: (2016-01-01)

Nuclease escape elements protect messenger RNA against cleavage by multiple viral endonucleases.
gan: Mandy Muller, et al.
Cyhoeddwyd: (2017-08-01)

Streptococcus pyogenes nuclease A (SpnA) mediated virulence does not exclusively depend on nuclease activity
gan: Callum Chalmers, et al.
Cyhoeddwyd: (2020-02-01)

Critical roles for ‘housekeeping’ nucleases in type III CRISPR-Cas immunity
gan: Lucy Chou-Zheng, et al.
Cyhoeddwyd: (2022-12-01)

Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease
gan: Youngbin Lim, et al.
Cyhoeddwyd: (2016-11-01)

1‐Hydroxy‐xanthine derivatives inhibit the human Caf1 nuclease and Caf1‐containing nuclease complexes via Mg2+‐dependent binding
gan: Blessing Airhihen, et al.
Cyhoeddwyd: (2019-04-01)

Identification of a novel nuclease activity in human DDX49 helicase
gan: Ashley J. Parkes, et al.
Cyhoeddwyd: (2024-12-01)

Targeting DNA repair nucleases in cancer
gan: Henderson, LR
Cyhoeddwyd: (2023)

Mutation detection using Surveyor™ nuclease
gan: Peter Qiu, et al.
Cyhoeddwyd: (2004-04-01)

Mechanism for nuclease regulation in RecBCD
gan: Martin Wilkinson, et al.
Cyhoeddwyd: (2016-09-01)

Taking U out, with two nucleases?
gan: Worthey Elizabeth A, et al.
Cyhoeddwyd: (2006-06-01)

Nucleases as molecular targets for cancer diagnosis
gan: Alien Balian, et al.
Cyhoeddwyd: (2021-11-01)

Phylogenomics of Cas4 family nucleases
gan: Sanjarbek Hudaiberdiev, et al.
Cyhoeddwyd: (2017-11-01)

Gene Editing in Human Lymphoid Cells: Role for Donor DNA, Type of Genomic Nuclease and Cell Selection Method
gan: Anastasia Zotova, et al.
Cyhoeddwyd: (2017-11-01)

Improvements of nuclease and nickase gene modification techniques for the treatment of genetic diseases
gan: Yaoyao Lu, et al.
Cyhoeddwyd: (2022-07-01)