Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin

Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin

BACKGROUND:Epidemiological studies suggest that metformin may reduce the incidence of cancer in patients with diabetes and multiple late phase clinical trials assessing the potential of repurposing this drug are underway. Transcriptomic profiling of tumour samples is an excellent tool to understand...

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Bibliographic Details
Main Authors: Lord, S, Collins, J, Cheng, W, Haider, S, Wigfield, S, Gaude, E, Fielding, B, Pinnick, K, Harjes, U, Segaran, A, Jha, P, Hoefler, G, Pollak, M, Thompson, A, Roy, P, English, R, Adams, R, Frezza, C, Buffa, F, Karpe, F, Harris, A
Format: Journal article
Language:English
Published: Nature Research 2019

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