IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.

Secreted factors from the epicardium are believed to be important in directing heart ventricular cardiomyocyte proliferation and morphogenesis, although the specific factors involved have not been identified or characterized adequately. We found that IGF2 is the most prominent mitogen made by primar...

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Bibliographic Details
Main Authors: Li, P, Cavallero, S, Gu, Y, Chen, T, Hughes, J, Hassan, A, Brüning, J, Pashmforoush, M, Sucov, H
Format: Journal article
Language:English
Published: 2011