Insights on the regeneration potential of Müller glia in the mammalian retina

Insights on the regeneration potential of Müller glia in the mammalian retina

Müller glia, the major glial cell types in the retina, maintain retinal homeostasis and provide structural support to retinal photoreceptors. They also possess regenerative potential that might be used for retinal repair in response to injury or disease. In teleost fish (such as zebrafish), the Müll...

Full description

Bibliographic Details
Main Authors:	Salman, A, McClements, ME, MacLaren, RE
Format:	Journal article
Language:	English
Published:	MDPI 2021

Similar Items

Minicircle delivery to the neural retina as a gene therapy approach
by: Staurenghi, F, et al.
Published: (2022)

Non-viral delivery of CRIPSR/Cas cargo to the retina using nanoparticles: current possibilities, challenges, and limitations
by: Salman, A, et al.
Published: (2022)

Cell-mediated inflammatory response to AAV gene therapy in the retina
by: Chandler, LC, et al.
Published: (2020)

Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina
by: Chandler, LC, et al.
Published: (2021)

Muller glia factors induce survival and neuritogenesis of peripheral and central neurons.
by: de Melo Reis, R, et al.
Published: (2008)

Development and role of retinal glia in regeneration of ganglion cells following retinal injury.
by: Maclaren, R
Published: (1996)

Inclusion of the woodchuck hepatitis virus posttranscriptional regulatory element enhances AAV2-driven transduction of mouse and human retina
by: Patrício, M, et al.
Published: (2017)

In silico analysis of pathogenic CRB1 single nucleotide variants and their amenability to base editing as a potential lead for therapeutic intervention
by: Bellingrath, J-S, et al.
Published: (2021)

RNA editing for Usher syndrome using CRISPR-Cas13
by: Fry, LE, et al.
Published: (2020)

RNA editing as a therapeutic approach for retinal gene therapy requiring long coding sequences
by: Fry, LE, et al.
Published: (2020)

Gene therapy for retinal disease.
by: McClements, M, et al.
Published: (2013)

Adeno-associated virus (AAV) dual vector strategies for gene therapy encoding large transgenes
by: McClements, M, et al.
Published: (2017)

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina
by: Hickey, DG, et al.
Published: (2017)

Is subretinal AAV gene replacement still the only viable treatment option for choroideremia?
by: Han, RC, et al.
Published: (2021)

Gene Therapies in Clinical Development to Treat Retinal Disorders
by: McClements, ME, et al.
Published: (2024)

Promoter orientation within an AAV-CRISPR vector affects Cas9 expression and gene editing efficiency
by: Fry, LE, et al.
Published: (2020)

Envisioning the development of a CRISPR-Cas mediated base editing strategy for a patient with a novel pathogenic CRB1 single nucleotide variant
by: Bellingrath, J-S, et al.
Published: (2022)

Chiasmatic specificity in the regenerating mammalian optic nerve.
by: Maclaren, R, et al.
Published: (1997)

A critical period for axon regrowth through a lesion in the developing mammalian retina.
by: Maclaren, R, et al.
Published: (1995)

Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration
by: Fry, LE, et al.
Published: (2025)

Association of a novel intronic variant in RPGR with hypomorphic phenotype of x-linked retinitis pigmentosa
by: Cehajic-Kapetanovic, J, et al.
Published: (2020)

Regeneration of the retina by stem cell transplantation therapy
by: Singh, M
Published: (2013)

Mirtron-mediated RNA knockdown/replacement therapy for the treatment of dominant retinitis pigmentosa
by: Orlans, HO, et al.
Published: (2021)

Immunomodulatory effects of hydroxychloroquine and chloroquine in viral infections and their potential application in retinal gene therapy
by: Chandler, L, et al.
Published: (2020)

Genome-editing strategies for treating human retinal degenerations
by: Quinn, J, et al.
Published: (2021)

The electroretinogram as a method for studying circadian rhythms in the mammalian retina.
by: Cameron, M, et al.
Published: (2008)

Max Müller
by: Crick, M
Published: (1972)

CDHR1-related late-onset macular dystrophy: further insights
by: Yusuf, IH, et al.
Published: (2020)

Regeneration in the developing optic nerve: correlating observations in the opossum to other mammalian systems.
by: Maclaren, R, et al.
Published: (1997)

A fragmented adeno-associated viral dual vector strategy for treatment of diseases caused by mutations in large genes leads to expression of hybrid transcripts
by: McClements, M, et al.
Published: (2016)

Stem cell therapy and the retina.
by: Maclaren, R, et al.
Published: (2007)

Purinergic signalling in neuron-glia interactions /
by: Chadwick, Derek, et al.
Published: (2006)

Tetradecanoylphorbol-13-acetate (TPA) significantly increases AAV2/5 transduction of human neuronal cells in vitro
by: You, Q, et al.
Published: (2012)

Melanopsin-dependent photoreception provides earliest light detection in the mammalian retina.
by: Sekaran, S, et al.
Published: (2005)

Diurnal and circadian regulation of connexin 36 transcript and protein in the mammalian retina.
by: Katti, C, et al.
Published: (2013)

Single-cell transcriptomic analysis of retinal immune regulation and blood-retinal barrier function during experimental autoimmune uveitis
by: Quinn, J, et al.
Published: (2024)

Gene therapy for age-related macular degeneration
by: MacLaren, RE
Published: (2015)

Epicardial signalling in mammalian heart regeneration
by: Masters, M
Published: (2015)

Quantum Reed-Muller codes
by: Steane, A
Published: (1999)

Complexity Bounds for Muller Games
by: Dawar, A, et al.
Published: (2011)