Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model
Although there is growing evidence for a role of excess intracellular cations, particularly calcium ions, in neuronal and glial cell injury in multiple sclerosis, as well as in non-inflammatory neurological conditions, the molecular mechanisms involved are not fully determined. We previously showed...
Prif Awduron: | Vergo, S, Craner, M, Etzensperger, R, Attfield, K, Friese, M, Newcombe, J, Esiri, M, Fugger, L |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2011
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Eitemau Tebyg
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Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model.
gan: Vergo, S, et al.
Cyhoeddwyd: (2011) -
ASIC1 expression contributes to demyelination and axonal injury in EAE and MS
gan: Vergo, S, et al.
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Acid sensing ion channel 1 contributes to axonal degeneration in autoimmune CNS inflammation and provides a novel target for neuroprotection in multiple sclerosis
gan: Craner, M, et al.
Cyhoeddwyd: (2008) -
Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system.
gan: Friese, M, et al.
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The contribution of demyelination to axonal loss in multiple sclerosis
gan: DeLuca, G, et al.
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