Novel small-molecule inhibitors of arylamine N-acetyltransferases: drug discovery by high-throughput screening.

Novel small-molecule inhibitors of arylamine N-acetyltransferases: drug discovery by high-throughput screening.

Arylamine N-acetyltransferases (NATs) are a family of enzymes found in eukaryotes and prokaryotes. While the precise endogenous function of NAT remains unknown for most organisms, recent evidence has shown that the expression of human NAT1 is up-regulated in estrogen receptor positive breast cancer....

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Detalhes bibliográficos
Main Authors:	Westwood, I, Kawamura, A, Russell, A, Sandy, J, Davies, S, Sim, E
Formato:	Journal article
Idioma:	English
Publicado em:	2011

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