Novel small-molecule inhibitors of arylamine N-acetyltransferases: drug discovery by high-throughput screening.

Arylamine N-acetyltransferases (NATs) are a family of enzymes found in eukaryotes and prokaryotes. While the precise endogenous function of NAT remains unknown for most organisms, recent evidence has shown that the expression of human NAT1 is up-regulated in estrogen receptor positive breast cancer....

詳細記述

書誌詳細
主要な著者: Westwood, I, Kawamura, A, Russell, A, Sandy, J, Davies, S, Sim, E
フォーマット: Journal article
言語:English
出版事項: 2011