Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells.
There is no reliable means of detecting latent M. tuberculosis infection, and even in patients with active tuberculosis, infection is often unconfirmed. We hypothesized that M. tuberculosis antigen-specific T cells might reliably indicate infection. We enumerated peripheral blood-derived interferon...
Main Authors: | Lalvani, A, Pathan, A, Mcshane, H, Wilkinson, R, Latif, M, Conlon, C, Pasvol, G, Hill, A |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2001
|
Similar Items
-
Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells.
by: Lalvani, A, et al.
Published: (2001) -
Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians.
by: Lalvani, A, et al.
Published: (2001) -
High frequencies of circulating IFN-gamma-secreting CD8 cytotoxic T cells specific for a novel MHC class I-restricted Mycobacterium tuberculosis epitope in M. tuberculosis-infected subjects without disease.
by: Pathan, A, et al.
Published: (2000) -
Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment.
by: Pathan, A, et al.
Published: (2001) -
Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis.
by: Lalvani, A, et al.
Published: (1998)