Modulation of THP-1 macrophage and cholesterol-loaded foam cell apolipoprotein E levels by glycosphingolipids.

Modulation of THP-1 macrophage and cholesterol-loaded foam cell apolipoprotein E levels by glycosphingolipids.

Macrophages synthesize and secrete apolipoprotein E (apoE) constitutively. This process is upregulated under conditions of cholesterol loading. The response to cholesterol is antiatherogenic as it is believed to promote cholesterol efflux from the artery wall. The concentration of lactosyl ceramide...

書誌詳細
主要な著者:	Garner, B, Mellor, H, Butters, T, Dwek, R, Platt, F
フォーマット:	Journal article
言語:	English
出版事項:	2002

類似資料

Increased glycosphingolipid levels in serum and aortae of apolipoprotein E gene knockout mice.
著者:: Garner, B, 等
出版事項: (2002)

Increased glycosphingolipid levels in serum and aortae of apolipoprotein E gene knockout mice
著者:: Brett Garner, 等
出版事項: (2002-02-01)

Apolipoprotein A-I promotes cholesterol release and apolipoprotein E recruitment from THP-1 macrophage-like foam cells
著者:: John K. Bielicki, 等
出版事項: (1999-01-01)

New therapeutics for the treatment of glycosphingolipid lysosomal storage diseases.
著者:: Butters, T, 等
出版事項: (2003)

Inhibition of glycosphingolipid biosynthesis: application to lysosomal storage disorders.
著者:: Butters, T, 等
出版事項: (2000)

Cellular effects of deoxynojirimycin analogues: uptake, retention and inhibition of glycosphingolipid biosynthesis.
著者:: Mellor, H, 等
出版事項: (2004)

Glycosphingolipid lysosomal storage diseases: therapy and pathogenesis.
著者:: Jeyakumar, M, 等
出版事項: (2002)

New developments in treating glycosphingolipid storage diseases.
著者:: Platt, F, 等
出版事項: (2005)

N-butyldeoxygalactonojirimycin: a more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin, in vitro and in vivo.
著者:: Andersson, U, 等
出版事項: (2000)

Glycosphingolipid profiling of tissues from mouse models of human lysosomal storage disorders
著者:: Priestman, D, 等
出版事項: (2008)

Reduction of plasma glycosphingolipid levels has no impact on atherosclerosis in apolipoprotein E-null mice
著者:: Elias N. Glaros, 等
出版事項: (2008-08-01)

Pharmacological impairment of acrosome formation and sperm head morphogenesis reveals essential role of glycosphingolipids in spermiogenesis
著者:: van der Spoel, A, 等
出版事項: (2002)

Substrate deprivation: a new therapeutic approach for the glycosphingolipid lysosomal storage diseases.
著者:: Platt, F, 等
出版事項: (2000)

Glycosphingolipid disorders of the brain.
著者:: Boomkamp, S, 等
出版事項: (2008)

Molecular requirements of imino sugars for the selective control of N-linked glycosylation and glycosphingolipid biosynthesis
著者:: Butters, T, 等
出版事項: (2000)

The apo E gene knockout mouse as a model to study the potential atherogenic properties of glycosphingolipids
著者:: Garner, B, 等
出版事項: (2003)

Lysosomal storage of oligosaccharide and glycosphingolipid in imino sugar treated cells.
著者:: Boomkamp, S, 等
出版事項: (2010)

Complement Factor H and Apolipoprotein E Participate in Regulation of Inflammation in THP-1 Macrophages
著者:: Eija Nissilä, 等
出版事項: (2018-11-01)

Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling.
著者:: Neville, D, 等
出版事項: (2004)

Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases
著者:: Silk, J, 等
出版事項: (2005)

Walnut oil increases cholesterol efflux through inhibition of stearoyl CoA desaturase 1 in THP-1 macrophage-derived foam cells
著者:: Gillies Peter J, 等
出版事項: (2011-08-01)

THP-1 macrophage cholesterol efflux is impaired by palmitoleate through Akt activation.
著者:: Jenika D Marshall, 等
出版事項: (2020-01-01)

Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases.
著者:: Gadola, S, 等
出版事項: (2006)

Involvement of caveolin-1 in cholesterol enrichment of high density lipoprotein during its assembly by apolipoprotein and THP-1 cells
著者:: Reijiro Arakawa, 等
出版事項: (2000-12-01)

Effects of cellular cholesterol loading on macrophage foam cell lysosome acidifications⃞
著者:: Brian E. Cox, 等
出版事項: (2007-05-01)

Glycosphingolipids in endocytic membrane transport.
著者:: Sillence, D, 等
出版事項: (2004)

Recombinant Klotho protein enhances cholesterol efflux of THP-1 macrophage-derived foam cells via suppressing Wnt/β-catenin signaling pathway
著者:: Wei Liu, 等
出版事項: (2020-03-01)

Diverse endogenous antigens for mouse NKT cells: self-antigens that are not glycosphingolipids.
著者:: Pei, B, 等
出版事項: (2011)

Probucol treatment is associated with an ABCA1-independent mechanism of cholesterol efflux to lipid poor apolipoproteins from foam cell macrophages
著者:: Anouar Hafiane, MSc, PhD, 等
出版事項: (2021-01-01)

Regulation of macrophage apolipoprotein E gene expression by cholesterol.
著者:: T Mazzone, 等
出版事項: (1989-07-01)

Introduction: Glycosphingolipids in cell biology and disease.
著者:: Sillence, D, 等
出版事項: (2004)

Membrane disruption and cytotoxicity of hydrophobic N-alkylated imino sugars is independent of the inhibition of protein and lipid glycosylation.
著者:: Mellor, H, 等
出版事項: (2003)

FHL2 regulates THP-1 macrophage foaming through NF-κB signaling pathway
著者:: CHEN Weiwei, LIAO Huang, SHI Zhenhong, LUO Ying
出版事項: (2024-02-01)

Ion Transport Modulators Differentially Modulate Inflammatory Responses in THP-1-Derived Macrophages
著者:: Steven C. Mitini-Nkhoma, 等
出版事項: (2021-01-01)

Modulator Effect of AT1 Receptor Knockdown on THP-1 Macrophage Proinflammatory Activity
著者:: Lourdes Nallely Acevedo-Villavicencio, 等
出版事項: (2024-05-01)

Substrate reduction therapy for glycosphingolipid storage disorders.
著者:: Lachmann, R, 等
出版事項: (2001)

Apoptotic modification of glycosphingolipids of human granulocytes
著者:: A. M. Tomin, 等
出版事項: (2012-09-01)

Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected].
著者:: Muindi, K, 等
出版事項: (2010)

Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport.
著者:: te Vruchte, D, 等
出版事項: (2004)

Hydroxychloroquine Effects on THP-1 Macrophage Cholesterol Handling: Cell Culture Studies Corresponding to the TARGET Cardiovascular Trial
著者:: Saba Ahmed, 等
出版事項: (2022-09-01)