Identification of FGF receptor-binding peptides for cancer gene therapy

Linear FGF receptor-binding heptapeptides were identified by phage display using sequential rounds of biopanning against cells with displacement of phage by FGF2. The consensus motif MXXP was iterated after four to five rounds and the peptide MQLPLAT was studied in depth. Phage bearing MQLPLAT showe...

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Bibliographic Details
Main Authors: Maruta, F, Parker, AL, Fisher, KD, Hallissey, MT, Ismail, T, Rowlands, DC, Chandler, LA, Kerr, DJ, Seymour, LW
Format: Journal article
Language:English
Published: Springer Nature 2002