N-acyl 'Quat' pyrrolidinone auxiliary as a chiral amide equivalent via direct aminolysis

A novel route into chiral amides is achieved through the efficient, non-racemising, cleavage of N-acyl side chains from a 'Quat' pyrrolidinone chiral auxiliary using a range of N-nucleophiles.

Bibliographic Details
Main Authors: Davies, S, Dixon, D
Format: Journal article
Language:English
Published: 1998
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author Davies, S
Dixon, D
author_facet Davies, S
Dixon, D
author_sort Davies, S
collection OXFORD
description A novel route into chiral amides is achieved through the efficient, non-racemising, cleavage of N-acyl side chains from a 'Quat' pyrrolidinone chiral auxiliary using a range of N-nucleophiles.
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spelling oxford-uuid:09979f06-7dac-475b-8783-7fb4a0b5e5322022-03-26T09:19:10ZN-acyl 'Quat' pyrrolidinone auxiliary as a chiral amide equivalent via direct aminolysisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:09979f06-7dac-475b-8783-7fb4a0b5e532EnglishSymplectic Elements at Oxford1998Davies, SDixon, DA novel route into chiral amides is achieved through the efficient, non-racemising, cleavage of N-acyl side chains from a 'Quat' pyrrolidinone chiral auxiliary using a range of N-nucleophiles.
spellingShingle Davies, S
Dixon, D
N-acyl 'Quat' pyrrolidinone auxiliary as a chiral amide equivalent via direct aminolysis
title N-acyl 'Quat' pyrrolidinone auxiliary as a chiral amide equivalent via direct aminolysis
title_full N-acyl 'Quat' pyrrolidinone auxiliary as a chiral amide equivalent via direct aminolysis
title_fullStr N-acyl 'Quat' pyrrolidinone auxiliary as a chiral amide equivalent via direct aminolysis
title_full_unstemmed N-acyl 'Quat' pyrrolidinone auxiliary as a chiral amide equivalent via direct aminolysis
title_short N-acyl 'Quat' pyrrolidinone auxiliary as a chiral amide equivalent via direct aminolysis
title_sort n acyl quat pyrrolidinone auxiliary as a chiral amide equivalent via direct aminolysis
work_keys_str_mv AT daviess nacylquatpyrrolidinoneauxiliaryasachiralamideequivalentviadirectaminolysis
AT dixond nacylquatpyrrolidinoneauxiliaryasachiralamideequivalentviadirectaminolysis