Global Genetic Architecture of an Erythroid Quantitative Trait Locus, HMIP-2.

Global Genetic Architecture of an Erythroid Quantitative Trait Locus, HMIP-2.

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HMIP-2 is a human quantitative trait locus affecting peripheral numbers, size and hemoglobin composition of red blood cells, with a marked effect on the persistence of the fetal form of hemoglobin, HbF, in adults. The locus consists of multiple common variants in an enhancer region for MYB (chr 6q23...

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Bibliographic Details
Main Authors: Menzel, S, Rooks, H, Zelenika, D, Mtatiro, SN, Gnanakulasekaran, A, Drasar, E, Cox, S, Liu, L, Masood, M, Silver, N, Garner, C, Vasavda, N, Howard, J, Makani, J, Adekile, A, Pace, B, Spector, T, Farrall, M, Lathrop, M, Thein, S
Format: Journal article
Language:English
Published: 2014

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