Intranasal lentiviral vector-mediated antibody delivery confers reduction of SARS-CoV-2 infection in elderly and immunocompromised mice

Intranasal lentiviral vector-mediated antibody delivery confers reduction of SARS-CoV-2 infection in elderly and immunocompromised mice

Vaccines for COVID-19 are now a crucial public health need, but the degree of protection provided by conventional vaccinations for individuals with compromised immune systems is unclear. The use of viral vectors to express neutralizing monoclonal antibodies (mAbs) in the lung is an alternative appro...

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Bibliographic Details
Main Authors:	Du, Y, Zhang, S, Zhang, Z, Miah, KM, Wei, P, Zhang, L, Zhu, Y, Li, Z, Ye, F, Gill, DR, Hyde, SC, Wang, Y, Zhao, J
Format:	Journal article
Language:	English
Published:	Frontiers Media 2022

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