The effect of sample size on polygenic hazard models for prostate cancer

The effect of sample size on polygenic hazard models for prostate cancer

We determined the effect of sample size on performance of polygenic hazard score (PHS) models in prostate cancer. Age and genotypes were obtained for 40,861 men from the PRACTICAL consortium. The dataset included 201,590 SNPs per subject, and was split into training and testing sets. Established-SNP...

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Bibliographic Details
Main Authors:	Karunamuni, RA, Huynh-Le, M-P, Fan, CC, Key, TJ, Travis, RC, Neal, DE, Hamdy, FC, Mills, IG, The PRACTICAL Consortium
Format:	Journal article
Language:	English
Published:	Springer Nature 2020

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