Impact of apolipoprotein(a) isoform size on lipoprotein(a) lowering in the HPS2-THRIVE study

<h4>Background</h4> <p>Genetic studies have shown lipoprotein(a) (Lp[a]) to be an important causal risk factor for coronary disease. Apolipoprotein(a) isoform size is the chief determinant of Lp(a) levels, but its impact on the benefits of therapies that lower Lp(a) remains unclea...

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Главные авторы: Parish, S, Hopewell, J, Hill, M, Marcovina, S, Valdes-Marquez, E, Haynes, R, Offer, A, Pedersen, T, Baigent, C, Collins, R, Landray, M, Armitage, J
Формат: Journal article
Язык:English
Опубликовано: American Heart Association 2018