Back-priming mode of phi6 RNA-dependent RNA polymerase.
The RNA-dependent RNA polymerase of the double-stranded RNA bacteriophage phi6 is capable of primer-independent initiation, as are many RNA polymerases. The structure of this polymerase revealed an initiation platform, composed of a loop in the C-terminal domain (QYKW, aa 629-632), that was essentia...
Main Authors: | Laurila, MR, Salgado, P, Stuart, D, Grimes, J, Bamford, D |
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Format: | Journal article |
Language: | English |
Published: |
2005
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