Amino acid sensing by mTORC1: Intracellular transporters mark the spot.

Cell metabolism and growth are matched to nutrient availability via the amino acid-regulated mechanistic Target of Rapamycin Complex 1 (mTORC1). Transporters have emerged as important amino acid sensors controlling mTOR recruitment and activation at the surface of multiple intracellular compartment...

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Bibliographic Details
Main Authors: Goberdhan, D, Wilson, C, Harris, A
Format: Journal article
Language:English
Published: Cell Press 2016