Identification of Tyr58 as the proton donor in the aspartate-alpha-decarboxylase reaction.

The decarboxylation of L-aspartate by E. coli L-aspartate-alpha-decarboxylase (ADC) is shown to occur with retention of configuration; analysis of the protein structure identifies Tyr58 as the proton donor in the decarboxylation mechanism.

Xehetasun bibliografikoak
Egile Nagusiak: Saldanha, SA, Birch, L, Webb, M, Nabbs, B, von Delft, F, Smith, A, Abell, C
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2001
Deskribapena
Gaia:The decarboxylation of L-aspartate by E. coli L-aspartate-alpha-decarboxylase (ADC) is shown to occur with retention of configuration; analysis of the protein structure identifies Tyr58 as the proton donor in the decarboxylation mechanism.