Phosphorylation of BRN2 modulates its interaction with the Pax3 promoter to control melanocyte migration and proliferation.

MITF-M and PAX3 are proteins central to the establishment and transformation of the melanocyte lineage. They control various cellular mechanisms, including migration and proliferation. BRN2 is a POU domain transcription factor expressed in melanoma cell lines and is involved in proliferation and inv...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Berlin, I, Denat, L, Steunou, A, Puig, I, Champeval, D, Colombo, S, Roberts, K, Bonvin, E, Bourgeois, Y, Davidson, I, Delmas, V, Nieto, L, Goding, C, Larue, L
Μορφή: Journal article
Γλώσσα:English
Έκδοση: 2012