Phosphorylation of BRN2 modulates its interaction with the Pax3 promoter to control melanocyte migration and proliferation.

Phosphorylation of BRN2 modulates its interaction with the Pax3 promoter to control melanocyte migration and proliferation.

MITF-M and PAX3 are proteins central to the establishment and transformation of the melanocyte lineage. They control various cellular mechanisms, including migration and proliferation. BRN2 is a POU domain transcription factor expressed in melanoma cell lines and is involved in proliferation and inv...

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Bibliographic Details
Main Authors: Berlin, I, Denat, L, Steunou, A, Puig, I, Champeval, D, Colombo, S, Roberts, K, Bonvin, E, Bourgeois, Y, Davidson, I, Delmas, V, Nieto, L, Goding, C, Larue, L
Format: Journal article
Language:English
Published: 2012

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