Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection.

BACKGROUND: Controlled human malaria infection (CHMI) studies are a vital tool to accelerate vaccine and drug development. As CHMI trials are performed in a controlled environment, they allow unprecedented, detailed evaluation of parasite growth dynamics (PGD) and immunological responses. However, C...

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Bibliographic Details
Main Authors:	Hodgson, S, Juma, E, Salim, A, Magiri, C, Kimani, D, Njenga, D, Muia, A, Cole, A, Ogwang, C, Awuondo, K, Lowe, B, Munene, M, Billingsley, P, James, E, Gunasekera, A, Sim, B, Njuguna, P, Rampling, T, Richman, A, Abebe, Y, Kamuyu, G, Muthui, M, Elias, S, Molyneux, C, Gerry, S
Format:	Journal article
Language:	English
Published:	2014

Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection.

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