Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection.

Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection.

BACKGROUND: Controlled human malaria infection (CHMI) studies are a vital tool to accelerate vaccine and drug development. As CHMI trials are performed in a controlled environment, they allow unprecedented, detailed evaluation of parasite growth dynamics (PGD) and immunological responses. However, C...

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Bibliographic Details
Main Authors: Hodgson, S, Juma, E, Salim, A, Magiri, C, Kimani, D, Njenga, D, Muia, A, Cole, A, Ogwang, C, Awuondo, K, Lowe, B, Munene, M, Billingsley, P, James, E, Gunasekera, A, Sim, B, Njuguna, P, Rampling, T, Richman, A, Abebe, Y, Kamuyu, G, Muthui, M, Elias, S, Molyneux, C, Gerry, S
Format: Journal article
Language:English
Published: 2014

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