A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa

A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa

Artemisinin resistance (AR) emerged in South East Asia 13 years ago and the identification of the resistance conferring molecular marker, Plasmodium falciparum Kelch 13 (Pfk13), 7 years ago has provided an invaluable tool for monitoring AR in malaria endemic countries. Molecular Pfk13 surveillance r...

書誌詳細
主要な著者:	Ndwiga, L, Kimenyi, KM, Wamae, K, Osoti, V, Akinyi, M, Omedo, I, Ishengoma, DS, Duah-Quashie, N, Andagalu, B, Ghansah, A, Amambua-Ngwa, A, Tukwasibwe, S, Tessema, SK, Karema, C, Djimde, AA, Dondorp, AM, Raman, J, Snow, RW, Bejon, P, Ochola-Oyier, LI
フォーマット:	Journal article
言語:	English
出版事項:	Australian Society for Parasitology 2021

類似資料

No evidence of P. falciparum K13 artemisinin conferring mutations over a 24-year analysis in Coastal Kenya, but a near complete reversion to chloroquine wild type parasites
著者:: Wamae, K, 等
出版事項: (2019)

Targeted amplicon deep sequencing for monitoring antimalarial resistance markers in western Kenya
著者:: Osoti, V, 等
出版事項: (2022)

Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya
著者:: Osoti, V, 等
出版事項: (2025)

Understanding P. falciparum asymptomatic infections: a proposition for a transcriptomic approach
著者:: Kimenyi, KM, 等
出版事項: (2019)

Maintenance of high temporal Plasmodium falciparum genetic diversity and complexity of infection in asymptomatic and symptomatic infections in Kilifi, Kenya from 2007 to 2018
著者:: Kimenyi, KM, 等
出版事項: (2022)

The Plasmodium falciparum Rh5 invasion protein complex reveals an excess of rare variant mutations
著者:: Ndwiga, L, 等
出版事項: (2021)

Amplicon sequencing as a potential surveillance tool for complexity of infection and drug resistance markers in Plasmodium falciparum asymptomatic infections
著者:: Wamae, K, 等
出版事項: (2022)

Fitness costs and the rapid spread of kelch13-C580Y substitutions conferring artemisinin resistance
著者:: Nair, S, 等
出版事項: (2018)

Targeted Next Generation Sequencing for malaria research in Africa: current status and outlook
著者:: Ghansah, A, 等
出版事項: (2019)

Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations on the island of New Guinea
著者:: Miotto, O, 等
出版事項: (2020)

Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations in Papua New Guinea
著者:: Miotto, O, 等
出版事項: (2019)

Plasmodium falciparum artemisinin resistance monitoring in Sabah, Malaysia : in vivo therapeutic efficacy and kelch13 molecular marker surveillance
著者:: Grigg, Matthew J., 等
出版事項: (2019)

Plasmodium falciparum artemisinin resistance monitoring in Sabah, Malaysia: in vivo therapeutic efficacy and kelch13 molecular marker surveillance
著者:: Grigg, M, 等
出版事項: (2018)

Few Plasmodium falciparum merozoite ligand and erythrocyte receptor pairs show evidence of balancing selection
著者:: Ochola-Oyier, L, 等
出版事項: (2019)

Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based combination therapy use in Mpumalanga Province, South Africa (2001–2018)
著者:: Raman, J, 等
出版事項: (2019)

Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected
著者:: Kimenyi, KM, 等
出版事項: (2024)

Monitoring parasite diversity for malaria elimination in sub-Saharan Africa.
著者:: Ghansah, A, 等
出版事項: (2014)

Major subpopulations of Plasmodium falciparum in sub-Saharan Africa
著者:: Amambua-Ngwa, A, 等
出版事項: (2019)

Optimisation of purification of plasmodium falciparum Kelch13 protein for structural analysis
著者:: Seo, Gilia Min Li
出版事項: (2023)

Understanding substrate recruitment by BTB-Kelch family E3 ligases
著者:: Chen, Z
出版事項: (2019)

Application of loop-mediated isothermal amplification combined with lateral flow assay visualization of Plasmodium falciparum kelch 13 C580Y mutation for artemisinin resistance detection in clinical samples
著者:: Sanmoung, W, 等
出版事項: (2023)

Molecular markers for artemisinin and partner drug resistance in natural Plasmodium falciparum populations following increased insecticide treated net coverage along the slope of mount Cameroon: cross-sectional study
著者:: Apinjoh, T, 等
出版事項: (2017)

Transmission and age impact the risk of developing febrile malaria in children with asymptomatic Plasmodium falciparum parasitemia
著者:: Wamae, K, 等
出版事項: (2018)

Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance rates after artemisinin-based treatments—a WWARN individual patient data meta-analysis
著者:: Ashley, E, 等
出版事項: (2019)

Detection of mutated Plasmodium vivax Kelch propeller domain (PvK12) in Malaysian isolates
著者:: Shairah, Dzul, 等
出版事項: (2018)

Limited polymorphism of the Kelch propeller domain in P. malariae and P. ovale isolates from Thailand.
著者:: Nakeesathit, S, 等
出版事項: (2016)

Limited polymorphism of the Kelch propeller domain in Plasmodium malariae and P. ovale isolates from Thailand.
著者:: Nakeesathit, S, 等
出版事項: (2016)

Micro-epidemiological structuring of Plasmodium falciparum parasite populations in regions with varying transmission intensities in Africa
著者:: Omedo, I, 等
出版事項: (2017)

Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases.
著者:: Canning, P, 等
出版事項: (2013)

Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases.
著者:: Canning, P, 等
出版事項: (2013)

Prospective identification of malaria parasite genes under balancing selection.
著者:: Tetteh, K, 等
出版事項: (2009)

Triple artemisinin-based combination therapies for malaria – a new paradigm?
著者:: van der Pluijm, RW, 等
出版事項: (2020)

Artemisinin: current status.
著者:: White, N
出版事項: (1994)

Intrarectal artemisinin derivatives.
著者:: Nosten, F, 等
出版事項: (1998)

Artemisinin-based combinations.
著者:: Ashley, E, 等
出版事項: (2005)

A unique protein phosphatase with kelch-like domains (PPKL) in Plasmodium modulates ookinete differentiation, motility and invasion.
著者:: Guttery, D, 等
出版事項: (2012)

The design and evaluation of a mobile system for rapid diagnostic test interpretation
著者:: Park, C, 等
出版事項: (2021)

Is triple artemisinin-based combination therapy necessary for uncomplicated malaria?
著者:: van der Pluijm, RW, 等
出版事項: (2022)

Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa-Pun District, Northern Kayin State, Myanmar.
著者:: Bonnington, C, 等
出版事項: (2017)

Artemisinin-resistant malaria in Africa demands urgent action
著者:: Dhorda, M, 等
出版事項: (2024)