A fission yeast homolog of Int-6, the mammalian oncoprotein and eIF3 subunit, induces drug resistance when overexpressed.

A fission yeast homolog of Int-6, the mammalian oncoprotein and eIF3 subunit, induces drug resistance when overexpressed.

Through a screen to identify genes that induce multi-drug resistance when overexpressed, we have identified a fission yeast homolog of Int-6, a component of the human translation initiation factor eIF3. Disruption of the murine Int-6 gene by mouse mammary tumor virus (MMTV) has been implicated previ...

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Bibliographic Details
Main Authors:	Crane, R, Craig, R, Murray, R, Dunand-Sauthier, I, Humphrey, T, Norbury, C
Format:	Journal article
Language:	English
Published:	2000

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