Recognition of HLA-Cw4 but not HLA-Cw6 by the NK cell receptor killer cell Ig-like receptor two-domain short tail number 4.

Recognition of HLA-Cw4 but not HLA-Cw6 by the NK cell receptor killer cell Ig-like receptor two-domain short tail number 4.

NK cells are cytotoxic to virus-infected and tumor cells that have lost surface expression of class I MHC proteins. Target cell expression of class I MHC proteins inhibits NK cytotoxicity through binding to inhibitory NK receptors. In contrast, a similar family of activating NK receptors, characteri...

Полное описание

Библиографические подробности
Главные авторы:	Katz, G, Markel, G, Mizrahi, S, Arnon, T, Mandelboim, O
Формат:	Journal article
Язык:	English
Опубликовано:	2001

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