Helplessness as a strategy for avoiding antiglobulin responses to therapeutic monoclonal antibodies.
The antiglobulin (anti-Ig) response to therapeutic monoclonal antibodies (mAbs) poses a significant obstacle to their routine application in man. Whilst humanization has lessened the problem, repeated courses of humanized mAbs still sensitise some patients. Previous work suggested that unresponsiven...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1994
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