MICHELANGLo: sculpting protein views on web pages without coding

<p><strong>Motivation:</strong>&nbsp;The sharing of macromolecular structural information online by scientists is predominantly performed via 2D static images, since the embedding of interactive 3D structures in webpages is non-trivial. Whilst the technologies to do so exist, t...

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Main Authors: Ferla, MP, Pagnamenta, AT, Damerell, D, Taylor, JC, Marsden, BD
Format: Journal article
Language:English
Published: Oxford University Press 2020
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author Ferla, MP
Pagnamenta, AT
Damerell, D
Taylor, JC
Marsden, BD
author_facet Ferla, MP
Pagnamenta, AT
Damerell, D
Taylor, JC
Marsden, BD
author_sort Ferla, MP
collection OXFORD
description <p><strong>Motivation:</strong>&nbsp;The sharing of macromolecular structural information online by scientists is predominantly performed via 2D static images, since the embedding of interactive 3D structures in webpages is non-trivial. Whilst the technologies to do so exist, they are often only implementable with significant web coding experience.</p> <p><strong>Results:</strong>&nbsp;Michelaɴɢʟo is an accessible and open-source web-based application that supports the generation, customization and sharing of interactive 3D macromolecular visualizations for digital media without requiring programming skills. A PyMOL file, PDB file, PDB identifier code or protein/gene name can be provided to form the basis of visualizations using the NGL JavaScript library. Hyperlinks that control the view can be added to text within the page. Protein-coding variants can be highlighted to support interpretation of their potential functional consequences. The resulting visualizations and text can be customized and shared, as well as embedded within existing websites by following instructions and using a self-contained download. Michelaɴɢʟo allows researchers to move away from static images and instead engage, describe and explain their protein to a wider audience in a more interactive fashion.</p> <p><strong>Availability and implementation:</strong>&nbsp;Michelaɴɢʟo is hosted at michelanglo.sgc.ox.ac.uk. The Python code is freely available at&nbsp;https://github.com/thesgc/MichelaNGLo, along with documentations about its implementation.</p>
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spelling oxford-uuid:0b9b8ace-ed69-4baa-ad6b-beb7d4ae2da32022-03-26T09:30:22ZMICHELANGLo: sculpting protein views on web pages without codingJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:0b9b8ace-ed69-4baa-ad6b-beb7d4ae2da3EnglishSymplectic ElementsOxford University Press2020Ferla, MPPagnamenta, ATDamerell, DTaylor, JCMarsden, BD<p><strong>Motivation:</strong>&nbsp;The sharing of macromolecular structural information online by scientists is predominantly performed via 2D static images, since the embedding of interactive 3D structures in webpages is non-trivial. Whilst the technologies to do so exist, they are often only implementable with significant web coding experience.</p> <p><strong>Results:</strong>&nbsp;Michelaɴɢʟo is an accessible and open-source web-based application that supports the generation, customization and sharing of interactive 3D macromolecular visualizations for digital media without requiring programming skills. A PyMOL file, PDB file, PDB identifier code or protein/gene name can be provided to form the basis of visualizations using the NGL JavaScript library. Hyperlinks that control the view can be added to text within the page. Protein-coding variants can be highlighted to support interpretation of their potential functional consequences. The resulting visualizations and text can be customized and shared, as well as embedded within existing websites by following instructions and using a self-contained download. Michelaɴɢʟo allows researchers to move away from static images and instead engage, describe and explain their protein to a wider audience in a more interactive fashion.</p> <p><strong>Availability and implementation:</strong>&nbsp;Michelaɴɢʟo is hosted at michelanglo.sgc.ox.ac.uk. The Python code is freely available at&nbsp;https://github.com/thesgc/MichelaNGLo, along with documentations about its implementation.</p>
spellingShingle Ferla, MP
Pagnamenta, AT
Damerell, D
Taylor, JC
Marsden, BD
MICHELANGLo: sculpting protein views on web pages without coding
title MICHELANGLo: sculpting protein views on web pages without coding
title_full MICHELANGLo: sculpting protein views on web pages without coding
title_fullStr MICHELANGLo: sculpting protein views on web pages without coding
title_full_unstemmed MICHELANGLo: sculpting protein views on web pages without coding
title_short MICHELANGLo: sculpting protein views on web pages without coding
title_sort michelanglo sculpting protein views on web pages without coding
work_keys_str_mv AT ferlamp michelanglosculptingproteinviewsonwebpageswithoutcoding
AT pagnamentaat michelanglosculptingproteinviewsonwebpageswithoutcoding
AT damerelld michelanglosculptingproteinviewsonwebpageswithoutcoding
AT taylorjc michelanglosculptingproteinviewsonwebpageswithoutcoding
AT marsdenbd michelanglosculptingproteinviewsonwebpageswithoutcoding