Structure-function relationships of the extracellular domain of the autosomal dominant polycystic kidney disease-associated protein, polycystin-1.

Polycystin-1 (PC-1) is a member of a novel family of proteins that have a multidomain structure. Although the C-terminal intracellular segments have been extensively studied, mainly with respect to their putative involvement in cell signalling, the potential function of the extracellular domains has...

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Detalhes bibliográficos
Main Authors: Weston, B, Malhas, A, Price, R
Formato: Journal article
Idioma:English
Publicado em: 2003

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