Ultra-high field magnetic resonance spectroscopy in psychiatry
<p>The advantages of ultra-high-field (UHF≥7T) MR have been demonstrated in a variety of MR acquisition modalities. Magnetic resonance spectroscopy (MRS) can particularly benefit from substantial gains in signal-to-noise ratio (SNR) and spectral resolution at UHF, enabling the quantification...
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| Format: | Journal article |
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Frontiers Media
2017
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| _version_ | 1797053086047404032 |
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| author | Godlewska, B Clare, S Cowen, P Emir, U |
| author_facet | Godlewska, B Clare, S Cowen, P Emir, U |
| author_sort | Godlewska, B |
| collection | OXFORD |
| description | <p>The advantages of ultra-high-field (UHF≥7T) MR have been demonstrated in a variety of MR acquisition modalities. Magnetic resonance spectroscopy (MRS) can particularly benefit from substantial gains in signal-to-noise ratio (SNR) and spectral resolution at UHF, enabling the quantification of numerous metabolites including, glutamate, glutamine, glutathione and γ-aminobutyric acid that are relevant to psychiatric disorders. The aim of this review is to give an overview about the advantages and advances of UHF MRS and its application to psychiatric disorders. In order to provide a practical guide for potential applications of MRS at UHF, a literature review is given, surveying advantages and disadvantages of MRS at ultra-high-field (UHF). Key concepts, emerging technologies, practical considerations and applications of UHF MRS are provided. Second, the strength of UHF MRS is demonstrated using some examples of its application in psychiatric disorders. </p> |
| first_indexed | 2024-03-06T18:39:07Z |
| format | Journal article |
| id | oxford-uuid:0c4a8da5-73ed-4ac5-87a8-9358313fd2d1 |
| institution | University of Oxford |
| last_indexed | 2024-03-06T18:39:07Z |
| publishDate | 2017 |
| publisher | Frontiers Media |
| record_format | dspace |
| spelling | oxford-uuid:0c4a8da5-73ed-4ac5-87a8-9358313fd2d12022-03-26T09:34:04ZUltra-high field magnetic resonance spectroscopy in psychiatryJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:0c4a8da5-73ed-4ac5-87a8-9358313fd2d1Symplectic Elements at OxfordFrontiers Media2017Godlewska, BClare, SCowen, PEmir, U <p>The advantages of ultra-high-field (UHF≥7T) MR have been demonstrated in a variety of MR acquisition modalities. Magnetic resonance spectroscopy (MRS) can particularly benefit from substantial gains in signal-to-noise ratio (SNR) and spectral resolution at UHF, enabling the quantification of numerous metabolites including, glutamate, glutamine, glutathione and γ-aminobutyric acid that are relevant to psychiatric disorders. The aim of this review is to give an overview about the advantages and advances of UHF MRS and its application to psychiatric disorders. In order to provide a practical guide for potential applications of MRS at UHF, a literature review is given, surveying advantages and disadvantages of MRS at ultra-high-field (UHF). Key concepts, emerging technologies, practical considerations and applications of UHF MRS are provided. Second, the strength of UHF MRS is demonstrated using some examples of its application in psychiatric disorders. </p> |
| spellingShingle | Godlewska, B Clare, S Cowen, P Emir, U Ultra-high field magnetic resonance spectroscopy in psychiatry |
| title | Ultra-high field magnetic resonance spectroscopy in psychiatry |
| title_full | Ultra-high field magnetic resonance spectroscopy in psychiatry |
| title_fullStr | Ultra-high field magnetic resonance spectroscopy in psychiatry |
| title_full_unstemmed | Ultra-high field magnetic resonance spectroscopy in psychiatry |
| title_short | Ultra-high field magnetic resonance spectroscopy in psychiatry |
| title_sort | ultra high field magnetic resonance spectroscopy in psychiatry |
| work_keys_str_mv | AT godlewskab ultrahighfieldmagneticresonancespectroscopyinpsychiatry AT clares ultrahighfieldmagneticresonancespectroscopyinpsychiatry AT cowenp ultrahighfieldmagneticresonancespectroscopyinpsychiatry AT emiru ultrahighfieldmagneticresonancespectroscopyinpsychiatry |