Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment.

The growth and survival of myeloma cells is critically regulated by cells of the bone marrow microenvironment, including osteoblasts. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potent inducer of myeloma cell apoptosis, however, this antimyeloma activity is inhibited by ost...

詳細記述

書誌詳細
主要な著者: Locklin, R, Croucher, P, Russell, R, Edwards, C
フォーマット: Journal article
言語:English
出版事項: 2007