Peri-operative silent myocardial ischaemia and long-term adverse outcomes in non-cardiac surgical patients.

Two hundred and seventy-five non-cardiac surgical patients were recruited to determine risk factors associated with the development of postoperative cardiovascular complications during the first year after surgery. Patients underwent ambulatory electrocardiography pre- and postoperatively. There wer...

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Main Authors: Higham, H, Sear, J, Neill, F, Sear, Y, Foëx, P
Formato: Journal article
Idioma:English
Publicado: 2001
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author Higham, H
Sear, J
Neill, F
Sear, Y
Foëx, P
author_facet Higham, H
Sear, J
Neill, F
Sear, Y
Foëx, P
author_sort Higham, H
collection OXFORD
description Two hundred and seventy-five non-cardiac surgical patients were recruited to determine risk factors associated with the development of postoperative cardiovascular complications during the first year after surgery. Patients underwent ambulatory electrocardiography pre- and postoperatively. There were 34 adverse events over the whole study period. Twenty-four occurred within 6 months and the remaining 10 occurred between 6 and 12 months postoperatively. Silent myocardial ischaemia was associated with adverse outcome over both the first 6 months [OR 4.44 (95% CI 1.77-11.13)] and the whole study period [OR 2.81 (1.26-6.07)]. Other risk factors were: vascular surgery [OR 17.09 (2.67-351.44)], history of angina [OR 6.29 (2.21-17.62)], concurrent treatment with calcium entry blockers [OR 2.68 (1.03-6.93)] and smoking [OR 4.93 (2.00-12.02)]. None of these was a useful predictor of long-term outcome (between 6 and 12 months postsurgery). These results are at variance with other published data, but we conclude that monitoring for peri-operative silent myocardial ischaemia does not aid the prediction of long-term cardiovascular complications.
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spelling oxford-uuid:0c837e34-5a6d-49c8-bae4-72cf5b4d6fe62022-03-26T09:35:25ZPeri-operative silent myocardial ischaemia and long-term adverse outcomes in non-cardiac surgical patients.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:0c837e34-5a6d-49c8-bae4-72cf5b4d6fe6EnglishSymplectic Elements at Oxford2001Higham, HSear, JNeill, FSear, YFoëx, PTwo hundred and seventy-five non-cardiac surgical patients were recruited to determine risk factors associated with the development of postoperative cardiovascular complications during the first year after surgery. Patients underwent ambulatory electrocardiography pre- and postoperatively. There were 34 adverse events over the whole study period. Twenty-four occurred within 6 months and the remaining 10 occurred between 6 and 12 months postoperatively. Silent myocardial ischaemia was associated with adverse outcome over both the first 6 months [OR 4.44 (95% CI 1.77-11.13)] and the whole study period [OR 2.81 (1.26-6.07)]. Other risk factors were: vascular surgery [OR 17.09 (2.67-351.44)], history of angina [OR 6.29 (2.21-17.62)], concurrent treatment with calcium entry blockers [OR 2.68 (1.03-6.93)] and smoking [OR 4.93 (2.00-12.02)]. None of these was a useful predictor of long-term outcome (between 6 and 12 months postsurgery). These results are at variance with other published data, but we conclude that monitoring for peri-operative silent myocardial ischaemia does not aid the prediction of long-term cardiovascular complications.
spellingShingle Higham, H
Sear, J
Neill, F
Sear, Y
Foëx, P
Peri-operative silent myocardial ischaemia and long-term adverse outcomes in non-cardiac surgical patients.
title Peri-operative silent myocardial ischaemia and long-term adverse outcomes in non-cardiac surgical patients.
title_full Peri-operative silent myocardial ischaemia and long-term adverse outcomes in non-cardiac surgical patients.
title_fullStr Peri-operative silent myocardial ischaemia and long-term adverse outcomes in non-cardiac surgical patients.
title_full_unstemmed Peri-operative silent myocardial ischaemia and long-term adverse outcomes in non-cardiac surgical patients.
title_short Peri-operative silent myocardial ischaemia and long-term adverse outcomes in non-cardiac surgical patients.
title_sort peri operative silent myocardial ischaemia and long term adverse outcomes in non cardiac surgical patients
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AT searj perioperativesilentmyocardialischaemiaandlongtermadverseoutcomesinnoncardiacsurgicalpatients
AT neillf perioperativesilentmyocardialischaemiaandlongtermadverseoutcomesinnoncardiacsurgicalpatients
AT seary perioperativesilentmyocardialischaemiaandlongtermadverseoutcomesinnoncardiacsurgicalpatients
AT foexp perioperativesilentmyocardialischaemiaandlongtermadverseoutcomesinnoncardiacsurgicalpatients