Toll-like receptor activation during cutaneous allergen sensitization blocks development of asthma through IFN-gamma-dependent mechanisms.

Toll-like receptor activation during cutaneous allergen sensitization blocks development of asthma through IFN-gamma-dependent mechanisms.

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Toll-like receptors (TLRs) are pattern-recognition receptors that have a pivotal role as primary sensors of microbial products and as initiators of innate and adaptive immune responses. We investigated the role of TLR2, TLR3, and TLR4 activation during cutaneous allergen sensitization in the modulat...

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Bibliographic Details
Main Authors: Haapakoski, R, Karisola, P, Fyhrquist, N, Savinko, T, Lehtimäki, S, Wolff, H, Lauerma, A, Alenius, H
Format: Journal article
Language:English
Published: 2013

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