Dose-dependent nodal/smad signals pattern the early mouse embryo
Nodal signals in the early post-implantation stage embryo are essential to establish initial proximal-distal (P-D) polarity and generate the final anterior-posterior (A-P) body axis. Nodal signaling in the epiblast results in the phosphorylation of Smad2 in the overlying visceral endoderm necessary...
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Format: | Journal article |
Language: | English |
Published: |
Academic Press
2014
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