PH dependence of listeriolysin O aggregation and pore-forming ability

Listeriolysin O (LLO) is the major factor implicated in the escape of Listeria monocytogenes from the phagolysosome. It is the only representative of cholesterol-dependent cytolysins that exhibits pH-dependent activity. Despite intense studies of LLO pH-dependence, this feature of the toxin still re...

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Bibliographic Details
Main Authors: Bavdek, A, Kostanjšek, R, Antonini, V, Lakey, J, Dalla Serra, M, Gilbert, R, Anderluh, G
Format: Journal article
Language:English
Published: 2012