Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase.

Slični predmeti

• Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.
  od: Ren, J, i dr.
  Izdano: (2001)
• Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase.
  od: Ren, J, i dr.
  Izdano: (2008)
• Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors.
  od: Ren, J, i dr.
  Izdano: (2004)
• Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138.
  od: Ren, J, i dr.
  Izdano: (2006)
• Crystal structures of HIV-1 reverse transcriptase mutated at codons 100, 106 and 108 show nevirapine resistance is mediated via perturbation of interactions with Tyr181 or Tyr188
  od: Stammers, D, i dr.
  Izdano: (2002)