Variation in the ICAM1 gene is not associated with severe malaria phenotypes.

Evidence from autopsy and in vitro binding studies suggests that adhesion of erythrocytes infected with Plasmodium falciparum to the human host intercellular adhesion molecule (ICAM)-1 receptor is important in the pathogenesis of severe malaria. Previous association studies between polymorphisms in...

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Detalles Bibliográficos
Autores principales: Fry, A, Auburn, S, Diakite, M, Green, A, Richardson, A, Wilson, J, Jallow, M, Sisay-Joof, F, Pinder, M, Griffiths, M, Peshu, N, Williams, T, Marsh, K, Molyneux, M, Taylor, T, Rockett, K, Kwiatkowski, D
Formato: Journal article
Lenguaje:English
Publicado: 2008