Using canavanine resistance to measure mutation rates in Schizosaccharomyces pombe

<p>We constructed a panel of&nbsp;<em>S</em>.&nbsp;<em>pombe</em>&nbsp;strains expressing DNA polymerase &epsilon; variants associated with cancer, specifically POLES297F, POLEV411L, POLEL424V, POLES459F, and used these to compare mutation rates determin...

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Bibliographic Details
Main Authors: Pai, C-C, Heitzer, E, Bertrand, S, Toumazou, S, Humphrey, TC, Kearsey, SE
Format: Journal article
Language:English
Published: Public Library of Science 2023

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