Using canavanine resistance to measure mutation rates in Schizosaccharomyces pombe
<p>We constructed a panel of <em>S</em>. <em>pombe</em> strains expressing DNA polymerase ε variants associated with cancer, specifically POLES297F, POLEV411L, POLEL424V, POLES459F, and used these to compare mutation rates determin...
Main Authors: | Pai, C-C, Heitzer, E, Bertrand, S, Toumazou, S, Humphrey, TC, Kearsey, SE |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2023
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