The interleukin 22 pathway interacts with mutant KRAS to promote poor prognosis in colon cancer.

Purpose: The cytokine interleukin 22 (IL-22) promotes tumor progression in murine models of colorectal cancer (CRC). However, the clinical significance of IL-22 in human CRC remains unclear. We sought to determine whether the IL-22 pathway is associated with prognosis in human CRC, and to identify m...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: McCuaig, S, Barras, D, Mann, E, Friedrich, M, Bullers, SJ, Janney, A, Garner, LC, Domingo, E, Koelzer, VH, Delorenzi, M, Tejpar, S, Maughan, TS, West, NR, Powrie, F
التنسيق: Journal article
اللغة:English
منشور في: American Association for Cancer Research 2020