Tapasin enhances MHC class I peptide presentation according to peptide half-life.

Understanding how peptides are selected for presentation by MHC class I is crucial to vaccination strategies based on cytotoxic T lymphocyte priming. We have studied this selection of the MHC class I peptide repertoire in terms of the presentation of a series of individual peptides with a wide range...

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Main Authors: Howarth, M, Williams, A, Tolstrup, AB, Elliott, T
格式: Journal article
语言:English
出版: 2004