Use of run-in periods in randomized trials
A prerandomization run-in is a period between screening a potential trial participant and their being randomized. In a 2019 article in JAMA Network Open, Fukuoka et al1 evaluated whether a mobile phone education application and in-person counseling could increase physical activity in 210 study parti...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
American Medical Association
2020
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| Summary: | A prerandomization run-in is a period between screening a potential trial participant and their being randomized. In a 2019 article in JAMA Network Open, Fukuoka et al1 evaluated whether a mobile phone education application and in-person counseling could increase physical activity in 210 study participants. A prerandomization run-in was used to improve adherence and determine baseline physical activity levels of the participants. In this article, the advantages and limitations of run-in periods are reviewed. |
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