Preliminary experience using extracorporeal high-intensity focused ultrasound for the treatment of kidney and liver tumours
High-intensity focused ultrasound (HIFU) provides a potentially non-invasive alternative to conventional therapies. We have been using the extracorporeal ultrasound-guided Model-JC Tumor Therapy System (HAIFU™ Technology Co, China) in clinical trials to evaluate the safety and feasibility of treatin...
| Main Authors: | , , , , , , , |
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| Format: | Conference item |
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2005
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| _version_ | 1826259041334067200 |
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| author | Illing, R Kennedy, J Wu, F ter Haar, G Phillips, R Protheroe, A Middleton, MR Cranston, D |
| author_facet | Illing, R Kennedy, J Wu, F ter Haar, G Phillips, R Protheroe, A Middleton, MR Cranston, D |
| author_sort | Illing, R |
| collection | OXFORD |
| description | High-intensity focused ultrasound (HIFU) provides a potentially non-invasive alternative to conventional therapies. We have been using the extracorporeal ultrasound-guided Model-JC Tumor Therapy System (HAIFU™ Technology Co, China) in clinical trials to evaluate the safety and feasibility of treating renal and liver tumours. 30 patients have been treated (22 liver and 8 kidney tumours), all of whom were available for adverse event reporting. Of the 22 liver tumours, 20 are evaluable for response to treatment; 14 were followed up with magnetic resonance imaging (MRI) alone, and 6 with both MRI and histological resection. Evidence of ablation was seen in 20/20 (100%) cases radiologically, and 6/6 (100%) cases histologically. Of the 8 kidney tumours treated, 7 are evaluable; 2 were followed up with MRI alone, and 5 with both MRI and histological resection. Evidence of ablation was seen in 4/7 (57%) radiologically and 1/5 (20%) histologically. Mild, moderate or severe transient pain was reported by 16 (53%), 7 (23%) and 1 (3%) patients, respectively. Superficial skin toxicity was seen in 7 patients (23%). Renal function was unaffected, and all patients were fit for discharge from hospital the day after treatment. Early results show that this technique is feasible, and carries a low morbidity. © 2005 American Institute of Physics. |
| first_indexed | 2024-03-06T18:43:36Z |
| format | Conference item |
| id | oxford-uuid:0dbf1b0e-7f81-4b23-b0ff-275770dfdf3d |
| institution | University of Oxford |
| last_indexed | 2024-03-06T18:43:36Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:0dbf1b0e-7f81-4b23-b0ff-275770dfdf3d2022-03-26T09:42:09ZPreliminary experience using extracorporeal high-intensity focused ultrasound for the treatment of kidney and liver tumoursConference itemhttp://purl.org/coar/resource_type/c_5794uuid:0dbf1b0e-7f81-4b23-b0ff-275770dfdf3dSymplectic Elements at Oxford2005Illing, RKennedy, JWu, Fter Haar, GPhillips, RProtheroe, AMiddleton, MRCranston, DHigh-intensity focused ultrasound (HIFU) provides a potentially non-invasive alternative to conventional therapies. We have been using the extracorporeal ultrasound-guided Model-JC Tumor Therapy System (HAIFU™ Technology Co, China) in clinical trials to evaluate the safety and feasibility of treating renal and liver tumours. 30 patients have been treated (22 liver and 8 kidney tumours), all of whom were available for adverse event reporting. Of the 22 liver tumours, 20 are evaluable for response to treatment; 14 were followed up with magnetic resonance imaging (MRI) alone, and 6 with both MRI and histological resection. Evidence of ablation was seen in 20/20 (100%) cases radiologically, and 6/6 (100%) cases histologically. Of the 8 kidney tumours treated, 7 are evaluable; 2 were followed up with MRI alone, and 5 with both MRI and histological resection. Evidence of ablation was seen in 4/7 (57%) radiologically and 1/5 (20%) histologically. Mild, moderate or severe transient pain was reported by 16 (53%), 7 (23%) and 1 (3%) patients, respectively. Superficial skin toxicity was seen in 7 patients (23%). Renal function was unaffected, and all patients were fit for discharge from hospital the day after treatment. Early results show that this technique is feasible, and carries a low morbidity. © 2005 American Institute of Physics. |
| spellingShingle | Illing, R Kennedy, J Wu, F ter Haar, G Phillips, R Protheroe, A Middleton, MR Cranston, D Preliminary experience using extracorporeal high-intensity focused ultrasound for the treatment of kidney and liver tumours |
| title | Preliminary experience using extracorporeal high-intensity focused ultrasound for the treatment of kidney and liver tumours |
| title_full | Preliminary experience using extracorporeal high-intensity focused ultrasound for the treatment of kidney and liver tumours |
| title_fullStr | Preliminary experience using extracorporeal high-intensity focused ultrasound for the treatment of kidney and liver tumours |
| title_full_unstemmed | Preliminary experience using extracorporeal high-intensity focused ultrasound for the treatment of kidney and liver tumours |
| title_short | Preliminary experience using extracorporeal high-intensity focused ultrasound for the treatment of kidney and liver tumours |
| title_sort | preliminary experience using extracorporeal high intensity focused ultrasound for the treatment of kidney and liver tumours |
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