R-loop immunoprecipitation: a method to detect R-loop interacting factors

R-loops are non-B-DNA structures consisting of an RNA/DNA hybrid and a displaced single-stranded DNA. They arise during transcription and play important biological roles. However, perturbation of R-loop levels represents a source of DNA damage and genome instability resulting in human diseases, incl...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Beghè, C, Gromak, N
Aineistotyyppi: Book section
Kieli:English
Julkaistu: Springer 2022