R-loop immunoprecipitation: a method to detect R-loop interacting factors

R-loops are non-B-DNA structures consisting of an RNA/DNA hybrid and a displaced single-stranded DNA. They arise during transcription and play important biological roles. However, perturbation of R-loop levels represents a source of DNA damage and genome instability resulting in human diseases, incl...

詳細記述

書誌詳細
主要な著者: Beghè, C, Gromak, N
フォーマット: Book section
言語:English
出版事項: Springer 2022