R-loop immunoprecipitation: a method to detect R-loop interacting factors
R-loops are non-B-DNA structures consisting of an RNA/DNA hybrid and a displaced single-stranded DNA. They arise during transcription and play important biological roles. However, perturbation of R-loop levels represents a source of DNA damage and genome instability resulting in human diseases, incl...
Main Authors: | Beghè, C, Gromak, N |
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格式: | Book section |
語言: | English |
出版: |
Springer
2022
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