R-loop immunoprecipitation: a method to detect R-loop interacting factors

R-loop immunoprecipitation: a method to detect R-loop interacting factors

R-loops are non-B-DNA structures consisting of an RNA/DNA hybrid and a displaced single-stranded DNA. They arise during transcription and play important biological roles. However, perturbation of R-loop levels represents a source of DNA damage and genome instability resulting in human diseases, incl...

Полное описание

Библиографические подробности
Главные авторы:	Beghè, C, Gromak, N
Формат:	Book section
Язык:	English
Опубликовано:	Springer 2022

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