R-loop immunoprecipitation: a method to detect R-loop interacting factors

R-loops are non-B-DNA structures consisting of an RNA/DNA hybrid and a displaced single-stranded DNA. They arise during transcription and play important biological roles. However, perturbation of R-loop levels represents a source of DNA damage and genome instability resulting in human diseases, incl...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Beghè, C, Gromak, N
स्वरूप: Book section
भाषा:English
प्रकाशित: Springer 2022