R-loop immunoprecipitation: a method to detect R-loop interacting factors
R-loops are non-B-DNA structures consisting of an RNA/DNA hybrid and a displaced single-stranded DNA. They arise during transcription and play important biological roles. However, perturbation of R-loop levels represents a source of DNA damage and genome instability resulting in human diseases, incl...
Hoofdauteurs: | , |
---|---|
Formaat: | Book section |
Taal: | English |
Gepubliceerd in: |
Springer
2022
|