Single domain intracellular antibodies: a minimal fragment for direct in vivo selection of antigen-specific intrabodies.
There is a major need in target validation and therapeutic applications for molecules that can interfere with protein function inside cells. Intracellular antibodies (intrabodies) can bind to specific targets in cells but isolation of intrabodies is currently difficult. Intrabodies are normally sing...
Main Authors: | Tanaka, T, Lobato, M, Rabbitts, T |
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Format: | Journal article |
Language: | English |
Published: |
2003
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